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Tandem mass spectrometry reveals the quaternary organization of macromolecular assemblies.

Abstract:

The application of mass spectrometry (MS) to the study of progressively larger and more complex macromolecular assemblies is proving increasingly useful for structural biologists. The scope of this approach has recently been widened through the application of a tandem MS procedure. This two-step technique involves the selection of specific assemblies in the gas phase and inducing their dissociation through collisions with argon atoms. Here, we investigate the mechanism of this process and sho...

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Publication status:
Published

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Journal:
Chemistry and biology More from this journal
Volume:
13
Issue:
6
Pages:
597-605
Publication date:
2006-06-01
DOI:
EISSN:
1879-1301
ISSN:
1074-5521
Language:
English
Keywords:
Pubs id:
pubs:59292
UUID:
uuid:90346796-f928-4ca1-994d-85cbe6da1cba
Local pid:
pubs:59292
Source identifiers:
59292
Deposit date:
2012-12-19

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