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Incorporating biologic measurements (SF(2), CFE) into a tumor control probability model increases their prognostic significance: a study in cervical carcinoma treated with radiation therapy.

Abstract:

PURPOSE: To assess whether incorporation of measurements of surviving fraction at 2 Gy (SF(2)) and colony-forming efficiency (CFE) into a tumor control probability (tcp) model increases their prognostic significance. METHODS AND MATERIALS: Measurements of SF(2) and CFE were available from a study on carcinoma of the cervix treated with radiation alone. These measurements, as well as tumor volume, dose, and treatment time, were incorporated into a Poisson tcp model (tcp(alpha,rho)). Regression...

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Journal:
International journal of radiation oncology, biology, physics
Volume:
50
Issue:
5
Pages:
1113-1122
Publication date:
2001-08-05
DOI:
EISSN:
1879-355X
ISSN:
0360-3016
URN:
uuid:8ffd2411-8f1c-49e6-8afc-36165e3bc795
Source identifiers:
275904
Local pid:
pubs:275904

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