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Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions

Abstract:
A photochemical approach to polysubstituted heterocycles using UV‐induced alkene isomerization is described. The method allows for the synthesis of disubstituted furans and pyrroles under mild and neutral conditions and also provides access to a class of trisubstituted furans pertinent to natural‐product synthesis. The method has broad functional‐group tolerance and many richly decorated heterocycles have been prepared incorporating functional groups that are unstable under Brønsted and Lewis acidic conditions.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/chem.201903590

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Oxford college:
Magdalen College
Role:
Author


Publisher:
Wiley
Journal:
Chemistry - A European Journal More from this journal
Volume:
25
Issue:
57
Pages:
13114-13118
Publication date:
2019-08-07
Acceptance date:
2019-08-07
DOI:
EISSN:
1521-3765
ISSN:
0947-6539


Language:
English
Keywords:
Pubs id:
pubs:1039338
UUID:
uuid:8f712a76-e7d8-4a8f-8f05-858c12c54f11
Local pid:
pubs:1039338
Source identifiers:
1039338
Deposit date:
2019-08-07
ARK identifier:

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