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Unexplained gastrointestinal symptoms: Think mitochondrial disease

Abstract:

Defects in mitochondrial function are increasingly recognised as central to the pathogenesis of many diseases, both inherited and acquired. Many of these mitochondrial defects arise from abnormalities in mitochondrial DNA and can result in multisystem disease, with gastrointestinal involvement common. Moreover, mitochondrial disease may present with a range of non-specific symptoms, and thus can be easily misdiagnosed, or even considered to be non-organic.We describe the clinical, histopathol...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.dld.2013.04.008

Authors


Chapman, TP More by this author
Fratter, C More by this author
Cullen, SN More by this author
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Publisher:
Elsevier Publisher's website
Journal:
Digestive and Liver Disease Journal website
Volume:
46
Issue:
1
Pages:
1-8
Publication date:
2014
DOI:
EISSN:
1878-3562
ISSN:
1590-8658
URN:
uuid:8f4d0bf3-6cbb-4013-9faf-8c9ff0ec1daa
Source identifiers:
448467
Local pid:
pubs:448467

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