Journal article
Compartmentalizing acid stress in bacteria
- Abstract:
- A Donnan equilibrium causes an influx of chloride ions into the Escherichia coli periplasm when the bacterium finds itself in gastric fluid. The combination of low pH and high anion concentration drives proteins to aggregate, a potentially lethal event unless prevented by specific chaperones.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 168.5KB, Terms of use)
-
- Publisher copy:
- 10.1038/s41589-018-0148-7
Authors
- Publisher:
- Nature Publishing Group
- Journal:
- Nature Chemical Biology More from this journal
- Volume:
- 14
- Issue:
- 11
- Pages:
- 993-994
- Publication date:
- 2018-10-15
- Acceptance date:
- 2018-09-14
- DOI:
- EISSN:
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1552-4469
- ISSN:
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1552-4450
- Pmid:
-
30323216
- Language:
-
English
- Pubs id:
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pubs:934991
- UUID:
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uuid:8ee44655-c3ab-4f8e-a8dd-e670515c848b
- Local pid:
-
pubs:934991
- Source identifiers:
-
934991
- Deposit date:
-
2018-12-19
Terms of use
- Copyright holder:
- Springer Nature Publishing AG
- Copyright date:
- 2018
- Notes:
- © 2018 Springer Nature Publishing AG. This is the accepted manuscript version of the article. The final version is available online from Nature Publishing Group at: https://doi.org/10.1038/s41589-018-0148-7
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