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Comparison of 1 + 5 DAT and 3 + 10 DAT followed by COAP or MAZE consolidation therapy in the treatment of acute myeloid leukemia: MRC ninth AML trial.

Abstract:

This trial, which will probably accrue over 1,000 patients before it closes, has already demonstrated that high remission rates are attainable in large multicenter studies using 'conventional' doses of ara-C. The results in the group aged less than 40 are comparable with many single-center studies. There is, at the moment, only a borderline difference in the remission rates between the two forms of induction therapy but the more intensive regimen of DAT 3 + 10 achieves remission more quickly ...

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Publication status:
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
Journal:
Seminars in oncology
Volume:
14
Issue:
2 Suppl 1
Pages:
32-36
Publication date:
1987-06-05
EISSN:
1532-8708
ISSN:
0093-7754
URN:
uuid:8e9582b9-f2d6-48aa-88da-d04782306832
Source identifiers:
109533
Local pid:
pubs:109533

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