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Journal article

Structure and methylation of the human calcitonin/alpha-CGRP gene.

Abstract:

We report a detailed analysis of the human calcitonin/alpha-CGRP gene locus. About 39kb of DNA containing the gene has been mapped and a common Pvu II RFLP identified downstream of the gene. DNA sequence analysis revealed an extensive CpG island containing several rare restriction enzyme sites at the 5' end of the gene. The structure of this island is unusual in that it contains two distinct CpG-rich regions, one located around exon 1 and the other about 1.5kb further upstream. Msp I sites wi...

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Publication status:
Published

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Publisher copy:
10.1093/nar/17.17.6999

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Nucleic acids research
Volume:
17
Issue:
17
Pages:
6999-7011
Publication date:
1989-09-01
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
Source identifiers:
31127
Language:
English
Keywords:
Pubs id:
pubs:31127
UUID:
uuid:8e51085a-09fc-4bca-a9a7-cb48cf8c38f6
Local pid:
pubs:31127
Deposit date:
2012-12-19

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