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d-Idose, d-Iduronic Acid, and d-Idonic Acid from d-Glucose via Seven-Carbon Sugars.

Abstract:
A practical synthesis of the very rare sugar d-idose and the stable building blocks for d-idose, d-iduronic, and d-idonic acids from ido-heptonic acid requires only isopropylidene protection, Shing silica gel-supported periodate cleavage of the C6-C7 bond of the heptonic acid, and selective reduction of C1 and/or C6. d-Idose is the most unstable of all the aldohexoses and a stable precursor which be stored and then converted under very mild conditions into d-idose is easily prepared.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/molecules24203758

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Oxford college:
Corpus Christi, Oriel College
Role:
Author
ORCID:
0000-0002-4853-2773
Publisher:
MDPI Publisher's website
Journal:
Molecules Journal website
Volume:
24
Issue:
20
Article number:
3758
Publication date:
2019-10-18
Acceptance date:
2019-10-16
DOI:
EISSN:
1420-3049
ISSN:
1420-3049
Pmid:
31635397
Language:
English
Keywords:
Pubs id:
pubs:1065282
UUID:
uuid:8e42708e-3c57-4f49-b617-88164909cfad
Local pid:
pubs:1065282
Source identifiers:
1065282
Deposit date:
2019-10-27

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