Journal article
Treatment-resistant depression and peripheral C-reactive protein
- Abstract:
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Introduction: Treatment-resistant depression (TRD) is a condition characterized by the absence of response to at least two adequate antidepressants, associated with neuroinflammatory alterations and dysfunctions in the hypothalamic-pituitary-adrenal (HPA) axis. Inflammatory biomarkers, such as interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and C-reactive protein (CRP), play a relevant role in the pathophysiology of this condition. Objective: To perform an integrative analysis on ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 478.2KB, Terms of use)
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- Publisher copy:
- 10.1192/bjp.2018.66
Authors
- Publisher:
- Cambridge University Press
- Journal:
- The British Journal of Psychiatry More from this journal
- Volume:
- 214
- Issue:
- 1
- Pages:
- 11-19
- Publication date:
- 2018-05-16
- DOI:
- EISSN:
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1472-1465
- ISSN:
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0007-1250
- Language:
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Portuguese
- Keywords:
- Pubs id:
-
853143
- Local pid:
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pubs:853143
- Source identifiers:
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W2949818647
- Deposit date:
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2025-11-26
- ARK identifier:
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Terms of use
- Copyright date:
- 2018
- Licence:
- CC Attribution (CC BY)
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