Journal article

In vivo assessments to detect antimalarial resistance

Abstract:: In vivo drug clinical trials are the gold standard for assessing the therapeutic efficacy of antimalarials. They must be conducted in a rigorous and standardized manner so that the resistance of antimalarial drugs can be compared both in time and in space. This chapter presents the methodology for conducting such clinical studies of antimalarials for the treatment of uncomplicated malaria and describes the logistical difficulties and limitations of this methodology. Finally it highlights the importance of such knowledge in preventing resistance, in prolonging the utility of existing antimalarial drugs, and in ensuring that all individuals and populations suffering from malaria get the right malaria treatment at the right time.

Publication status:: Published

Peer review status:: Peer reviewed

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Dhorda, M., & Dondorp, A. (2019). In vivo assessments to detect antimalarial resistance. Malaria Control and Elimination, 2013, 105–121.

MLA Style

Dhorda, M, and A Dondorp. “In Vivo Assessments to Detect Antimalarial Resistance.” Malaria Control and Elimination, Methods in Molecular Biology, vol. 2013, 2019, pp. 105–21.

Chicago Style

Dhorda, M, and A Dondorp. 2019. “In Vivo Assessments to Detect Antimalarial Resistance.” Malaria Control and Elimination, Methods in Molecular Biology, vol. 2013: 105–21.
Print

Access Document

Publisher copy:: 10.1007/978-1-4939-9550-9_8

Authors

+ Dhorda, M More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Role:: Author
ORCID:: 0000-0002-7849-3293

+ Dondorp, A More by this author

Institution:: University of Oxford
Department:: NDM
Sub department:: Tropical Medicine
Role:: Author

Publisher:: Humana Press
Journal:: Malaria Control and Elimination More from this journal
Volume:: 2013
Pages:: 105-121
Series:: Methods in Molecular Biology
Publication date:: 2019-07-03
DOI:: 10.1007/978-1-4939-9550-9_8
EISSN:: 1940-6029
ISSN:: 1064-3745
Pmid:: 31267497
ISBN:: 9781493995509

Language:: English
Keywords:: methodology

resistance

therapeutic efficacy study

malaria

FFR
Pubs id:: pubs:1031930
UUID:: uuid:8df98b10-2112-49c1-b61c-168e9d369d09
Local pid:: pubs:1031930
Source identifiers:: 1031930
Deposit date:: 2019-07-18
ARK identifier:: ark:/29072/ora_8df98b10211249c1b61c168e9d369d09

Terms of use

Copyright holder:: Springer Science+Business Media, LLC, part of Springer Nature
Copyright date:: 2019
Notes:: Copyright © 2019 Springer Science+Business Media, LLC, part of Springer Nature.

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

Views and downloads will return soon

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP