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Journal article

Modification of the release characteristics of estradiol encapsulated in PLGA particles via surface coating.

Abstract:

BACKGROUND: Drug-loaded poly(lactide-co-glycolide) particles (100-4500 nm in diameter) were prepared via the electrospraying method. An extensive study was then carried out to determine the parameters affecting the release profile of estradiol (the drug or active pharmaceutical ingredient) in order to facilitate minimum initial burst release of estradiol. RESULTS AND DISCUSSION: The three most important factors affecting estradiol release were identified as: particle size, coating of the par...

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Publisher copy:
10.4155/tde.11.154
Journal:
Therapeutic delivery More from this journal
Volume:
3
Issue:
2
Pages:
209-226
Publication date:
2012-02-01
DOI:
EISSN:
2041-6008
ISSN:
2041-5990
Language:
English
Keywords:
Pubs id:
pubs:327788
UUID:
uuid:8dbedc2a-281c-42ed-9ca6-bf63e26b98cc
Local pid:
pubs:327788
Source identifiers:
327788
Deposit date:
2013-11-16

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