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Thermo-responsive microcarriers based on poly(N-isopropylacrylamide)

Abstract:

Microcarrier cell culture systems provide an attractive alternative to the conventional monolayer cell culture for cell amplification, due to their high surface area-to-volume ratio. Unlike enzymatic methods for removing cells from microcarriers after cell culture, which can lead to irreversible damage of the cells, microcarriers which release cells by temperature adjustment have been developed. This was achieved by grafting a temperature-responsive polymer, poly(N-isopropylacrylamide) (PNIPA...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
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Engineering and Physical Sciences Research Council More from this funder
Publisher:
Elsevier Publisher's website
Journal:
European Polymer Journal Journal website
Volume:
67
Pages:
346-364
Publication date:
2015-06-01
DOI:
ISSN:
0014-3057
Source identifiers:
524553
Keywords:
Pubs id:
pubs:524553
UUID:
uuid:8d9e79c3-aaa5-437f-86ba-1a696d52880d
Local pid:
pubs:524553
Deposit date:
2015-08-24

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