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Thermo-responsive microcarriers based on poly(N-isopropylacrylamide)

Abstract:

Microcarrier cell culture systems provide an attractive alternative to the conventional monolayer cell culture for cell amplification, due to their high surface area-to-volume ratio. Unlike enzymatic methods for removing cells from microcarriers after cell culture, which can lead to irreversible damage of the cells, microcarriers which release cells by temperature adjustment have been developed. This was achieved by grafting a temperature-responsive polymer, poly(N-isopropylacrylamide) (PNIPA...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
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Engineering and Physical Sciences Research Council More from this funder
Publisher:
Elsevier Publisher's website
Journal:
European Polymer Journal Journal website
Volume:
67
Pages:
346-364
Publication date:
2015-06-05
DOI:
ISSN:
0014-3057
URN:
uuid:8d9e79c3-aaa5-437f-86ba-1a696d52880d
Source identifiers:
524553
Local pid:
pubs:524553

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