Journal article
Biomimetic spinning of artificial spider silk from a chimeric minispidroin.
- Abstract:
- Herein we present a chimeric recombinant spider silk protein (spidroin) whose aqueous solubility equals that of native spider silk dope and a spinning device that is based solely on aqueous buffers, shear forces and lowered pH. The process recapitulates the complex molecular mechanisms that dictate native spider silk spinning and is highly efficient; spidroin from one liter of bacterial shake-flask culture is enough to spin a kilometer of the hitherto toughest as-spun artificial spider silk fiber.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 3.9MB, Terms of use)
-
(Preview, Accepted manuscript, pdf, 10.0MB, Terms of use)
-
- Publisher copy:
- 10.1038/nchembio.2269
Authors
- Publisher:
- Nature Publishing Group
- Journal:
- Nature Chemical Biology More from this journal
- Volume:
- 13
- Issue:
- 3
- Pages:
- 262-264
- Publication date:
- 2017-01-01
- Acceptance date:
- 2016-10-25
- DOI:
- EISSN:
-
1552-4469
- ISSN:
-
1552-4450
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:671448
- UUID:
-
uuid:8d8aa985-18b7-4c52-8bab-24b6756690ae
- Local pid:
-
pubs:671448
- Source identifiers:
-
671448
- Deposit date:
-
2017-03-07
Terms of use
- Copyright holder:
- Nature America, Inc
- Copyright date:
- 2017
- Notes:
- © 2017 Nature America, Inc., part of Springer Nature. All rights reserved.
If you are the owner of this record, you can report an update to it here: Report update to this record