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Neurocognition, cerebellar functions and psychiatric features in spinocerebellar ataxia type 34: a case series

Abstract:

Objective: This study primarily aimed to comprehensively characterize the neurological, neuroradiological and neurocognitive profiles, as well psychiatric features of individuals with Spinocerebellar Ataxia Type 34 (SCA34) associated with pathogenic variants in the ELOVL4 gene. Secondarily, we investigated the relationship between neurocognitive functions and cerebellar morphology in individuals with SCA34 by correlating structural changes to cognitive performance. Given involvement of the ce...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fncom.2025.1710961

Authors


Publisher:
Frontiers Media
Journal:
Frontiers in Computational Neuroscience More from this journal
Volume:
19
Article number:
1710961
Publication date:
2025-12-09
Acceptance date:
2025-11-24
DOI:
EISSN:
1662-5188
ISSN:
1662-5188


Language:
English
Keywords:
UUID:
uuid_8d5d8057-233e-466b-b90b-14cc61564417
Source identifiers:
3588284
Deposit date:
2025-12-23
ARK identifier:
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