Journal article
The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis
- Abstract:
-
Background:To investigate small-nucleolar RNAs (snoRNAs) as reference genes when measuring miRNA expression in tumour samples, given emerging evidence for their role in cancer.Methods:Four snoRNAs, commonly used for normalisation, RNU44, RNU48, RNU43 and RNU6B, and miRNA known to be associated with pathological factors, were measured by real-time polymerase chain reaction in two patient series: 219 breast cancer and 46 head and neck squamous cell carcinoma (HNSCC). SnoRNA and miRNA were then ...
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Bibliographic Details
- Journal:
- British Journal of Cancer
- Volume:
- 104
- Issue:
- 7
- Pages:
- 1168-1177
- Publication date:
- 2011-03-29
- DOI:
- EISSN:
-
1532-1827
- ISSN:
-
0007-0920
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:135221
- UUID:
-
uuid:8d4686c4-4618-4a1c-b526-6716a42e45c7
- Local pid:
- pubs:135221
- Source identifiers:
-
135221
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2011
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