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Cardiac consequences of epileptic seizures in the tetanus neurotoxin model of temporal lobe epilepsy

Abstract:

Death is the most destructive outcome of epilepsy. Around 18% of deaths in those with epilepsy cannot be attributed to the disease itself; these deaths are collectively categorised as Sudden Unexplained Deaths in Epilepsy (SUDEP). Currently, the cause of SUDEP is hypothesised to involve seizure-induced respiratory or cardiac failure. Ictal (during seizure) central and obstructive apnoea, decreases in ictal oxygen saturation, changes in blood pressure, heart rate, autonomic control and card...

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Alexander Ashby-Lumsden More by this author

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Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English

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