Journal article
L-arginine and tetrahydrobiopterin protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease.
- Abstract:
-
Diminished levels of L-arginine and endothelial nitric oxide synthase (eNOS) uncoupling through deficiency of tetrahydrobiopterin (BH(4)) may contribute to endothelial dysfunction. We investigated the effect of L-arginine and BH(4) administration on ischemia-reperfusion (I/R)-induced endothelial dysfunction in patients with type 2 diabetes and coronary artery disease (CAD). Forearm blood flow was measured by venous occlusion plethysmography in 12 patients with type 2 diabetes or impaired gluc...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.atherosclerosis.2008.08.034
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Bibliographic Details
- Journal:
- Atherosclerosis
- Volume:
- 204
- Issue:
- 1
- Pages:
- 73-78
- Publication date:
- 2009-05-01
- DOI:
- EISSN:
-
1879-1484
- ISSN:
-
0021-9150
- Source identifiers:
-
105307
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:105307
- UUID:
-
uuid:8d08192e-0b80-48d3-a2ab-ddb64b2b939f
- Local pid:
- pubs:105307
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2009
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