Journal article icon

Journal article

Bayesian coestimation of phylogeny and sequence alignment

Abstract:

Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this problem is to first build a multiple alignment of these sequences, followed by a phylogenetic reconstruction step based on this multiple alignment. However, alignment and phylogenetic inference are fundamentally interdependent, and ignoring this fact leads to biased and overconf...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1186/1471-2105-6-83

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
Publisher:
BioMed Central
Journal:
BMC Bioinformatics More from this journal
Volume:
6
Article number:
83
Publication date:
2005-04-01
Acceptance date:
2005-04-01
DOI:
EISSN:
1471-2105
Language:
English
Keywords:
UUID:
uuid:8cc37574-7b61-430f-a53e-12cec75921b7
Local pid:
pubs:68193
Source identifiers:
68193
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP