Journal article
Bayesian coestimation of phylogeny and sequence alignment
- Abstract:
-
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this problem is to first build a multiple alignment of these sequences, followed by a phylogenetic reconstruction step based on this multiple alignment. However, alignment and phylogenetic inference are fundamentally interdependent, and ignoring this fact leads to biased and overconf...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Bioinformatics Journal website
- Volume:
- 6
- Article number:
- 83
- Publication date:
- 2005-04-01
- Acceptance date:
- 2005-04-01
- DOI:
- EISSN:
-
1471-2105
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:8cc37574-7b61-430f-a53e-12cec75921b7
- Local pid:
- pubs:68193
- Source identifiers:
-
68193
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Lunter et al
- Copyright date:
- 2005
- Notes:
- © 2005 Lunter et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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