Estimating reassortment rates in co-circulating Eurasian swine influenza viruses.

Journal article

Swine have often been considered as a mixing vessel for different influenza strains. In order to assess their role in more detail, we undertook a retrospective sequencing study to detect and characterize the reassortants present in European swine and to estimate the rate of reassortment between H1N1, H1N2 and H3N2 subtypes with Eurasian (avian-like) internal protein-coding segments. We analysed 69 newly obtained whole genome sequences of subtypes H1N1-H3N2 from swine influenza viruses sampled...

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Authors: Lycett, S; Baillie, G; Coulter, E; Bhatt, S; Kellam, P

• Publication status: Published
• Journal: Journal of general virology
• Volume: 93
• Issue: Pt 11
• Pages: 2326-2336
• Publication date: 2012-11-01
• DOI: 10.1099/vir.0.044503-0
• EISSN: 1465-2099
• ISSN: 0022-1317
• Language: English
• Keywords: Asia; Phylogeny; RNA, Viral; Swine Diseases; Combating Swine Influenza Initiative-COSI Consortium; Reassortant Viruses; Orthomyxoviridae Infections; Retrospective Studies; Neuraminidase; Influenza A virus; Hemagglutinins; Genotype; Swine; Real-Time Polymerase Chain Reaction; Europe; Molecular Sequence Data; Consensus Sequence; Pandemics; Genome, Viral; Likelihood Functions; Animals