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The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection

Abstract:

Human respiratory syncytial virus (hRSV) transmission dynamics are inherently cyclical, and the observed genetic diversity (between groups A and B) also appears to have a repeating pattern. A key unknown is the extent to which genetic variants interact immunologically, and thus impact on epidemiology. We developed a novel mathematical model for hRSV transmission including seasonal forcing of incidence and temporary intra- and inter-group partial immunity. Simu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1017/s0950268804003450

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Wadham College
Role:
Author
ORCID:
0000-0002-6523-185X
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Role:
Author
ORCID:
0000-0002-6747-0889
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Role:
Author
ORCID:
0000-0002-0030-7278
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Name:
Wellcome Trust
Grant:
061584
Publisher:
Cambridge University Press
Journal:
Epidemiology and Infection More from this journal
Volume:
133
Issue:
2
Pages:
279-289
Publication date:
2005-01-04
Acceptance date:
2004-11-01
DOI:
EISSN:
1469-4409
ISSN:
0950-2688
Pmid:
15816153
Language:
English
Keywords:
Pubs id:
pubs:449649
UUID:
uuid:8c95d787-ede0-4f15-a8a1-b23fbb79cb37
Local pid:
pubs:449649
Source identifiers:
449649
Deposit date:
2019-02-05

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