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Biocompatibility of fluids for multiphase drops-in-drops microfluidics

Abstract:

This paper addresses the biocompatibility of fluids and surfactants in the context of microfluidics and more specifically in a drops-in-drops system for mammalian cell based drug screening. In the drops-in-drops approach, three immiscible fluids are used to manipulate the flow of aqueous microliter-sized drops; it enables merging of drops containing cells with drops containing drugs within a Teflon tube. Preliminary tests showed that a commonly-used fluid and surfactant combination resulted i...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Brasenose College
Role:
Author
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Name:
Medical Research Council
Grant:
MR/K010867/1
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Name:
7th Framework Marie Curie Career Integration grant
Grant:
333848
More from this funder
Name:
Indonesian Endowment Fund for Education (LPDP)
Publisher:
Springer Verlag
Journal:
Biomedical Microdevices More from this journal
Volume:
18
Issue:
6
Publication date:
2016-12-05
Acceptance date:
2016-01-01
DOI:
EISSN:
1572-8781
ISSN:
1387-2176
Keywords:
Pubs id:
pubs:664903
UUID:
uuid:8c76b37d-2864-4b46-8502-7a3f090e7c4a
Local pid:
pubs:664903
Source identifiers:
664903
Deposit date:
2016-12-10

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