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Biocompatibility of fluids for multiphase drops-in-drops microfluidics

Abstract:

This paper addresses the biocompatibility of fluids and surfactants in the context of microfluidics and more specifically in a drops-in-drops system for mammalian cell based drug screening. In the drops-in-drops approach, three immiscible fluids are used to manipulate the flow of aqueous microliter-sized drops; it enables merging of drops containing cells with drops containing drugs within a Teflon tube. Preliminary tests showed that a commonly-used fluid and surfactant combination resulted i...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s10544-016-0137-0

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Department:
Oxford, MPLS, Engineering Science
Role:
Author
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Department:
Oxford, MSD, Pathology Dunn School
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Author
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Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Department:
Brasenose College
Role:
Author
Indonesian Endowment Fund for Education (LPDP) More from this funder
John Fell Fund More from this funder
Publisher:
Springer Verlag Publisher's website
Journal:
Biomedical Microdevices Journal website
Volume:
18
Issue:
6
Chapter number:
114
Publication date:
2016-12-05
Acceptance date:
2016-01-01
DOI:
EISSN:
1572-8781
ISSN:
1387-2176
Pubs id:
pubs:664903
URN:
uri:8c76b37d-2864-4b46-8502-7a3f090e7c4a
UUID:
uuid:8c76b37d-2864-4b46-8502-7a3f090e7c4a
Local pid:
pubs:664903
Paper number:
6

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