Journal article

Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platform

Abstract:: OBJECTIVE: To compare the effectiveness of sotrovimab (a neutralising monoclonal antibody) with molnupiravir (an antiviral) in preventing severe outcomes of covid-19 in adult patients infected with SARS-CoV-2 in the community and at high risk of severe outcomes from covid-19. DESIGN: Observational cohort study with the OpenSAFELY platform. SETTING: With the approval of NHS England, a real world cohort study was conducted with the OpenSAFELY-TPP platform (a secure, transparent, open source sof...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Zheng, B., Green, A. C. A., Tazare, J., Curtis, H. J., Fisher, L., Nab, L., Schultze, A., Mahalingasivam, V., Parker, E. P. K., Hulme, W. J., Bacon, S. C. J., DeVito, N. J., Bates, C., Evans, D., Inglesby, P., Drysdale, H., Davy, S., Cockburn, J., Morton, C. E., … Goldacre, B. (2022). Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platform. The BMJ, 379, e071932–e071932.

MLA Style

Zheng, B, et al. “Comparative Effectiveness of Sotrovimab and Molnupiravir for Prevention of Severe Covid-19 Outcomes in Patients in the Community: Observational Cohort Study with the OpenSAFELY Platform.” The BMJ, vol. 379, 2022, pp. e071932–e071932.

Chicago Style

Zheng, B, ACA Green, J Tazare, et al. 2022. “Comparative Effectiveness of Sotrovimab and Molnupiravir for Prevention of Severe Covid-19 Outcomes in Patients in the Community: Observational Cohort Study with the OpenSAFELY Platform.” The BMJ 379: e071932–e071932.
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Files:: Zheng_et_al_2022_Comparative_effectiveness_of.pdf

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Publisher copy:: 10.1136/bmj-2022-071932

Authors

+ Zheng, B More by this author

Role:: Author
ORCID:: 0000-0003-1814-6692

+ Green, ACA More by this author

Institution:: University of Oxford
Role:: Author
ORCID:: 0000-0002-7246-2074

+ Tazare, J More by this author

Role:: Author
ORCID:: 0000-0002-7194-2615

+ Curtis, HJ More by this author

Institution:: University of Oxford
Role:: Author
ORCID:: 0000-0003-3429-9576

+ Fisher, L More by this author

Institution:: University of Oxford
Role:: Author
ORCID:: 0000-0002-0295-3812

More authors...

+ Wellcome Trust More from this funder

Funder identifier:: 10.13039/100010269

Publisher:: BMJ
Journal:: The BMJ More from this journal
Volume:: 379
Pages:: e071932-e071932
Publication date:: 2022-11-16
Acceptance date:: 2022-10-06
DOI:: 10.1136/bmj-2022-071932
ISSN:: 1756-1833

Language:: English
Keywords:: Coronavirus disease 2019 (COVID-19)

Psychological intervention

Disease

Cohort

Internal medicine

Family medicine

Medicine

Observational study

Emergency medicine

Pediatrics

Retrospective cohort study

Cohort study

Infectious disease (medical specialty)
Pubs id:: 1304578
Local pid:: pubs:1304578
Source identifiers:: W4309515692
Deposit date:: 2026-04-29
ARK identifier:: ark:/29072/ora_8c307af62c004777a16e9ea81ee077b2

Terms of use

Copyright date:: 2022

Licence:: CC Attribution (CC BY)

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