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Journal article

Deep immune profiling of endometrial and peripheral blood cells in endometriosis

Abstract:
Study question:
How is endometrial and systemic immunity modulated throughout the menstrual cycle and are there changes in women with endometriosis?
Summary answer:
Endometriosis is associated with reduced endometrial early natural killer (NK) cells and increased mucosal-associated invariant T (MAIT)-like CD8+ T cells, with cyclical variation.
What is known already:
The endometrial mucosa contains innate and adaptive immune cel... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/humrep/deag090

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
ORCID:
0000-0002-5373-9939
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0002-1826-953X
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0003-4307-9161


More from this funder
Funder identifier:
https://ror.org/052gg0110
Grant:
0010398
More from this funder
Funder identifier:
https://ror.org/01gfj5k83


Publisher:
Oxford University Press
Journal:
Human Reproduction More from this journal
Article number:
deag090
Place of publication:
England
Publication date:
2026-06-05
Acceptance date:
2026-05-12
DOI:
EISSN:
1460-2350
ISSN:
0268-1161
Pmid:
42243626


Language:
English
Keywords:
Pubs id:
2429984
Local pid:
pubs:2429984
Source identifiers:
W7163667283
Deposit date:
2026-06-15
ARK identifier:

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