- Abstract:
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The ribosome is an evolutionarily conserved organelle essential for cellular function. Ribosome construction requires assembly of approximately 80 different ribosomal proteins (RPs) and four different species of rRNA. As RPs co-assemble into one multi-subunit complex, mutation of the genes that encode RPs might be expected to give rise to phenocopies, in which the same phenotype is associated with loss-of-function of each individual gene. However, a more complex picture is emerging in which, ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
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(pdf, 1.9MB)
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- Publisher copy:
- 10.1371/journal.pgen.1003094
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Publication date:
- 2013-01-31
- Acceptance date:
- 2012-09-30
- DOI:
- EISSN:
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1553-7404
- ISSN:
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1553-7390
- URN:
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uuid:8bfeb3f9-4e96-49e1-b52e-acc44a33d0cb
- Source identifiers:
-
384768
- Local pid:
- pubs:384768
- Copyright holder:
- Watkins-Chow et al.
- Copyright date:
- 2013
- Notes:
- © 2013 Watkins-Chow et al. This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. There is a correction to this article at https://doi.org/10.1371/journal.pgen.1005682
Journal article
Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes
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