Chemoselective debenzylation of N-benzyl tertiary amines with ceric ammonium nitrate

Journal article

Treatment of a range of N-benzyl tertiary amines with aqueous eerie ammonium nitrate results in N-debenzylation to afford the corresponding secondary amine. Chemoselective mono-W-debenzylation of N-benzyl tertiary amines is shown to occur in the presence of N-benzyl amides, O-benzyl ethers, O-benzyl esters, O-benzyl phenolates and 5-benzyl ethers. © The Royal Society of Chemistry 2000.

Authors: Bull, S; Davies, S; Fenton, G; Mulvaney, A; Prasad, R

• Publication status: Published
• Journal: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
• Issue: 22
• Pages: 3765-3774
• Publication date: 2000-01-01
• DOI: 10.1039/b006852g
• EISSN: 1364-5463
• ISSN: 1470-4358
• Language: English