Journal article
The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn’s disease
- Abstract:
-
Background & Aims: Recent data suggest that polymorphisms in the organic cation transporter (OCTN) genes OCTN1 (SLC22A4) and OCTN2 (SLC22A5) represent disease-causing mutations within the IBD5 locus (chromosome 5q31). We investigated associations with disease susceptibility, phenotype, and evidence for epistasis with CARD15 in 679 patients with Crohn’s disease (CD) or ulcerative colitis (UC).
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Methods: A total of 374 patients with CD, 305...
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Gastroenterology Journal website
- Volume:
- 129
- Issue:
- 6
- Pages:
- 1854-1864
- Publication date:
- 2005-12-12
- Acceptance date:
- 2005-09-07
- DOI:
- EISSN:
-
1528-0012
- ISSN:
-
0016-5085
- Pmid:
-
16344054
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:827903
- UUID:
-
uuid:8bada9c1-f180-42c4-a021-76cb299df5ed
- Local pid:
- pubs:827903
- Source identifiers:
-
827903
- Deposit date:
- 2018-08-09
Terms of use
- Copyright holder:
- American Gastroenterological Association
- Copyright date:
- 2005
- Notes:
- © 2005 American Gastroenterological Association. Published by Elsevier Inc. All rights reserved.
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