Activation of peripheral leukocytes in rat pregnancy and experimental preeclampsia.

Journal article

OBJECTIVE: The aim of this study was to search for activation markers of peripheral leukocytes in experimental preeclampsia in the rat. STUDY DESIGN: Experimental preeclampsia was induced in 14-day-pregnant rats by infusion of endotoxin (1.0 microg/kg body weight). For comparison, rats with normal pregnancies that were infused with sodium chloride solution and cyclic rats that were infused with either endotoxin or sodium chloride solution were used. At various points before and after the infu...

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Authors: Faas, M; Schuiling, G; Linton, E; Sargent, I; Redman, C

• Publication status: Published
• Journal: American journal of obstetrics and gynecology
• Volume: 182
• Issue: 2
• Pages: 351-357
• Publication date: 2000-02-01
• DOI: 10.1016/s0002-9378(00)70223-7
• EISSN: 1097-6868
• ISSN: 0002-9378
• Language: English
• Keywords: Leukocytes; Pregnancy; Granulocytes; Rats, Wistar; Male; L-Selectin; Animals; Female; Integrin alpha4; Flow Cytometry; Endotoxins; Monocytes; Pre-Eclampsia; Antigens, CD14; Lymphocytes; Antigens, CD; Rats; Antigens, CD11