Journal article
Iron deficiency anaemia in pregnancy: a contemporary review
- Abstract:
- Iron deficiency anaemia is a global health problem, which particularly affects pregnant women. Iron deficiency anaemia during pregnancy is associated with increased maternal and perinatal morbidity and mortality. Maternal iron deficiency may also be associated with neurocognitive deficits in infants. Iron requirements increase during pregnancy and are influenced by hepcidin, the master regulator of iron homeostasis. The enduring global burden of maternal anaemia suggests that currently employed iron supplementation strategies are suboptimal. Recent developments in our understanding of systemic and placental iron homeostasis may improve therapeutic effectiveness by altering the dose and frequency of oral iron. Intravenous iron appears to be a safe treatment to correct maternal anaemia rapidly but research on patient-centred outcomes and cost-effectiveness is needed. Future trials should be adequately powered to assess outcomes relevant to pregnant women.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Preview, Accepted manuscript, 1003.8KB, Terms of use)
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- Publisher copy:
- 10.1177/1753495x20932426
Authors
- Publisher:
- SAGE Publications
- Journal:
- Obstetric Medicine More from this journal
- Volume:
- 14
- Issue:
- 2
- Pages:
- 67-76
- Publication date:
- 2020-07-07
- Acceptance date:
- 2020-05-13
- DOI:
- EISSN:
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1753-4968
- ISSN:
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1753-495X
- Language:
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English
- Keywords:
- Pubs id:
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1117262
- Local pid:
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pubs:1117262
- Deposit date:
-
2020-07-09
Terms of use
- Copyright holder:
- Benson et al.
- Copyright date:
- 2020
- Rights statement:
- © The Author(s) 2020.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from SAGE Publications at: https://doi.org/10.1177/1753495X20932426
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