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Treatment of chronic hepatitis C virus infection in Rwanda with ledipasvir-sofosbuvir (SHARED): a single-arm trial.

Abstract:

BACKGROUND: Limited treatment data are available for hepatitis C virus (HCV) in sub-Saharan Africa, especially for genotype 4. Our objective was to establish the safety and efficacy of ledipasvir-sofosbuvir for chronic HCV genotype 1 or 4 infection in adults in Rwanda.

METHODS: We did a single-arm trial to evaluate the safety and efficacy of ledipasvir-sofosbuvir in Rwandan adults with chronic HCV infection at a single study site (Rwanda Military H...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Elsevier
Journal:
Lancet Gastroenterology and Hepatology More from this journal
Volume:
4
Issue:
2
Pages:
119-126
Publication date:
2019-02-01
Acceptance date:
2018-11-01
DOI:
ISSN:
2468-1253
Pmid:
30552056
Language:
English
Pubs id:
pubs:954637
UUID:
uuid:8ac53e52-c6c5-4a78-98a7-0128fb2c2530
Local pid:
pubs:954637
Source identifiers:
954637
Deposit date:
2019-08-25

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