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A new model of temporary focal neocortical ischemia in the rat.

Abstract:

BACKGROUND AND PURPOSE: We describe a new rat model of temporary focal ischemia that produces neocortical ischemia without the need for prolonged anesthesia. METHODS: Temporary focal cerebral ischemia was initiated during halothane anesthesia, maintained for varying periods without anesthesia, and reversed by clip removal requiring brief anesthesia. Tandem carotid and middle cerebral artery occlusion for 1-4 hours and permanent occlusion were used to determine the duration and extent of ische...

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Publication status:
Published

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Publisher copy:
10.1161/01.str.23.2.273

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Stroke and Geratology
Role:
Author
Journal:
Stroke; a journal of cerebral circulation
Volume:
23
Issue:
2
Pages:
273-279
Publication date:
1992-02-01
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Source identifiers:
80204
Language:
English
Keywords:
Pubs id:
pubs:80204
UUID:
uuid:8ac17847-0759-41ac-86b8-6e2fd7bf343c
Local pid:
pubs:80204
Deposit date:
2012-12-19

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