Journal article
The importance of dead material within a tumour on the dynamics in response to radiotherapy
- Abstract:
-
In vivo tumours are highly heterogeneous, often comprising regions of hypoxia and necrosis. Radiotherapy significantly alters the intratumoural composition. Moreover, radiation-induced cell death may occur via a number of different mechanisms that act over different timescales. Dead material may therefore occupy a significant portion of the tumour volume for some time after irradiation and may affect the subsequent tumour dynamics.
We present a three phase tumour growth model that ...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- IOP Publishing Publisher's website
- Journal:
- Physics in Medicine and Biology Journal website
- Volume:
- 65
- Issue:
- 1
- Article number:
- 015007
- Publication date:
- 2019-10-08
- Acceptance date:
- 2019-10-08
- DOI:
- EISSN:
-
1361-6560
- ISSN:
-
0031-9155
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1061339
- UUID:
-
uuid:8a9330d5-96da-46f3-b029-a655fcc04324
- Local pid:
- pubs:1061339
- Source identifiers:
-
1061339
- Deposit date:
- 2019-10-08
Terms of use
- Copyright holder:
- Institute of Physics and Engineering in Medicine
- Copyright date:
- 2020
- Rights statement:
- © 2020 Institute of Physics and Engineering in Medicine.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from IOP Publishing at: https://doi.org/10.1088/1361-6560/ab4c27
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record