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Journal article

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Abstract:

To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease.Mendelian randomisation meta-analysis of 56 epidemiological studies.261 991 individuals of European descent, including 20 259 coronary heart disease cases and 10 164 stroke events. Data were available on ADH1B rs1229984 variant, alcohol phenotypes, and cardiovascular biomarkers.Odds ratio for coronary heart disease and stroke associated...

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Publication status:
Published

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Publisher copy:
10.1136/bmj.g4164

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
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Journal:
BMJ (Clinical research ed.)
Volume:
349
Issue:
jul10 6
Pages:
g4164
Publication date:
2014-01-01
DOI:
EISSN:
1756-1833
ISSN:
0959-8138
Source identifiers:
475908
Language:
English
Keywords:
Pubs id:
pubs:475908
UUID:
uuid:8a815a94-0023-44ce-966c-63110ac0634d
Local pid:
pubs:475908
Deposit date:
2014-07-24

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