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Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials.

Abstract:

BACKGROUND: Subgroup analyses in randomized trials examine whether effects of interventions differ between subgroups of study populations according to characteristics of patients or interventions. However, findings from subgroup analyses may be misleading, potentially resulting in suboptimal clinical and health decision making. Few studies have investigated the reporting and conduct of subgroup analyses and a number of important questions remain unanswered. The objectives of this study are: 1...

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Publication status:
Published

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Publisher copy:
10.1186/1745-6215-10-101

Authors


Journal:
Trials More from this journal
Volume:
10
Issue:
1
Pages:
101
Publication date:
2009-01-01
DOI:
EISSN:
1745-6215
ISSN:
1745-6215
Language:
English
Keywords:
Pubs id:
pubs:219038
UUID:
uuid:8a6f0868-4b10-40f0-8e89-99df8e923dc4
Local pid:
pubs:219038
Source identifiers:
219038
Deposit date:
2013-11-16

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