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Sulfur amino acids in methionine-restricted rats: hyperhomocysteinemia.

Abstract:

OBJECTIVE: Dietary methionine restriction in Fischer-344 rats favorably influences visceral fat mass, insulin sensitivity, metabolic parameters, and longevity. However, little is known about the effects of methionine restriction on serum methionine and its downstream sulfur amino acids. We investigated the serum sulfur amino acid profile of male Fischer-344 rats fed a methionine-restricted diet for 3 mo. METHODS AND RESULTS: Using tandem mass spectrometry, we observed marked reduction in ser...

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Publication status:
Published

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Publisher copy:
10.1016/j.nut.2009.09.017

Authors


Journal:
Nutrition (Burbank, Los Angeles County, Calif.) More from this journal
Volume:
26
Issue:
11-12
Pages:
1201-1204
Publication date:
2010-01-01
DOI:
EISSN:
1873-1244
ISSN:
0899-9007
Language:
English
Keywords:
Pubs id:
pubs:195502
UUID:
uuid:8a40a3b5-9d25-4834-8d85-83df7a182600
Local pid:
pubs:195502
Source identifiers:
195502
Deposit date:
2012-12-19

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