Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties.

Faleri, A; Santini, L; Brier, S; Pansegrau, W; Lo Surdo, P; Scarselli, M; Buricchi, F; Volpini, G; Genovese, A; van der Veen, S; Lea, S; Tang, C; Savino, S; Pizza, M; Finco, O; Norais, N; Masignani, V

Journal article

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties.

Abstract:: Factor H binding protein (fHbp) is one of the main antigens of the 4-component meningococcus B (4CMenB) multicomponent vaccine against disease caused by serogroup B Neisseria meningitidis (MenB). fHbp binds the complement down-regulating protein human factor H (hfH), thus resulting in immune evasion. fHbp exists in 3 variant groups with limited cross-protective responses. Previous studies have described the generation of monoclonal antibodies (mAbs) targeting variant-specific regions of fHbp....
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Publication status:: Published

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APA Style

Faleri, A., Santini, L., Brier, S., Pansegrau, W., Lo Surdo, P., Scarselli, M., Buricchi, F., Volpini, G., Genovese, A., van der Veen, S., Lea, S., Tang, C., Savino, S., Pizza, M., Finco, O., Norais, N., & Masignani, V. (2014). Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 28(4), 1644–1653.

MLA Style

Faleri, A., et al. “Two Cross-Reactive Monoclonal Antibodies Recognize Overlapping Epitopes on Neisseria Meningitidis Factor H Binding Protein but Have Different Functional Properties.” FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, vol. 28, no. 4, 2014, pp. 1644–53.

Chicago Style

Faleri, A, L Santini, S Brier, W Pansegrau, P Lo Surdo, M Scarselli, F Buricchi, et al. 2014. “Two Cross-Reactive Monoclonal Antibodies Recognize Overlapping Epitopes on Neisseria Meningitidis Factor H Binding Protein but Have Different Functional Properties.” FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 28 (4): 1644–53.
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