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Predictors of the rate of cognitive decline in older adults using machine learning

Abstract:

This thesis presents a comprehensive framework for studying Alzheimer's Disease (AD) progression by focusing on the classification of AD, Mild Cognitive Impairment (MCI), and Cognitively Normal (CN) individuals using advanced machine learning models that analyze changes in brain volumetrics over time through MRI scans. In the first phase of the research, MR images from the Alzheimer's Disease Neuroimaging Initiative database were utilized, which included sequences of 3-4 scans taken annually ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1371/journal.pone.0280029

Authors

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Role:
Author
ORCID:
0000-0002-8600-6539
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-9977-8888
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Role:
Author
ORCID:
0000-0001-5775-7053
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Role:
Author
ORCID:
0000-0001-7549-9545


Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
18
Issue:
3
Pages:
e0280029-e0280029
Publication date:
2023-03-03
DOI:
EISSN:
1932-6203
ISSN:
1932-6203


Language:
English
Keywords:
Pubs id:
1667848
Local pid:
pubs:1667848
Source identifiers:
W4323031833
Deposit date:
2026-06-08
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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