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Journal article : Review

Viral vector vaccines

Abstract:
Over the past two years, the SARS-CoV-2 pandemic has highlighted the impact that emerging pathogens can have on global health. The development of new and effective vaccine technologies is vital in the fight against such threats. Viral vectors are a relatively new vaccine platform that relies on recombinant viruses to deliver selected immunogens into the host. In response to the SARS-CoV-2 pandemic, the development and subsequent rollout of adenoviral vector vaccines has shown the utility, impact, scalability and efficacy of this platform. Shown to elicit strong cellular and humoral immune responses in diverse populations, these vaccine vectors will be an important approach against infectious diseases in the future.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.coi.2022.102210

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
ORCID:
0000-0002-6902-9886
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
ORCID:
0000-0001-7711-897X
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Oxford college:
St Cross College
Role:
Author
ORCID:
0000-0001-7361-719X


Publisher:
Elseveir
Journal:
Current Opinion in Immunology More from this journal
Volume:
77
Article number:
102210
Publication date:
2022-05-25
Acceptance date:
2022-04-15
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
Pmid:
35643023


Language:
English
Keywords:
Subtype:
Review
Pubs id:
1263718
Local pid:
pubs:1263718
Deposit date:
2022-08-09
ARK identifier:

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