- Abstract:
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The use of placebos in randomised controlled trials is a subject of considerable ethical debate. In this paper we present a set of considerations to evaluate the ethics of placebo controlled trials that includes: social value of the study; need for a randomised controlled trial and placebo; standards of care; risks of harm due to administration of placebo and the harm benefit balance; clinical equipoise; and double standards. We illustrate the application of... - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 354.6kb)
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- Publisher copy:
- 10.1186/s12910-018-0259-4
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- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Medical Ethics Journal website
- Volume:
- 19
- Pages:
- Article: 19
- Publication date:
- 2018-03-06
- Acceptance date:
- 2018-02-26
- DOI:
- EISSN:
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1472-6939
- ISSN:
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1472-6939
- Pubs id:
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pubs:828719
- URN:
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uri:899fbec9-2135-4e89-a6d5-7a53517a0dbb
- UUID:
-
uuid:899fbec9-2135-4e89-a6d5-7a53517a0dbb
- Local pid:
- pubs:828719
- Language:
- English
- Keywords:
- Copyright holder:
- Cheah et al.
- Copyright date:
- 2018
- Notes:
- © The Author(s) 2018. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
Journal article
The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial
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