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Journal article

Revisiting the diet-heart hypothesis: critical appraisal of the Minnesota Coronary Experiment.

Abstract:

Several articles have concluded that associations between high cholesterol and premature death are lacking and advocate for revision of current guidance advising low consumption (<10%) of saturated fat. Ramsden and colleagues recovered 45 year old data from the Minnesota Coronary Experiment, a randomised controlled trial conducted in state mental hospitals and nursing homes in Minnesota, USA, and reassessed the effect of a diet rich in linoleic acid on serum cholesterol and mortality. The authors found that the diet lowered total cholesterol but did not reduce the risk of premature mortality and might even have increased it.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmj.j2108

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Oxford college:
Trinity College
Role:
Author


Publisher:
BMJ Publishing Group
Journal:
BMJ More from this journal
Volume:
357
Pages:
j2108
Publication date:
2017-06-01
DOI:
EISSN:
1756-1833
ISSN:
0959-8138
Pmid:
28572081


Language:
English
Keywords:
Pubs id:
pubs:700838
UUID:
uuid:88eada84-ca2a-4532-a368-a19d9505a661
Local pid:
pubs:700838
Source identifiers:
700838
Deposit date:
2018-01-05

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