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A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study

Abstract:

BACKGROUND. Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid used in multiple sclerosis and intractable epilepsies. Preclinical studies show CBD has numerous cardiovascular benefits, including a reduced blood pressure (BP) response to stress. The aim of this study was to investigate if CBD reduces BP in humans.

METHODS. Nine healthy male volunteers were given 600 mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study. Cardiovascular parameter...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1172/jci.insight.93760

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Publisher:
American Society for Clinical Investigation Publisher's website
Journal:
JCI insight Journal website
Volume:
2
Issue:
12
Publication date:
2017-06-15
Acceptance date:
2017-04-28
DOI:
ISSN:
2379-3708
Pubs id:
pubs:701352
UUID:
uuid:884ee917-ba30-4bc9-b2e3-19c55692ead5
Local pid:
pubs:701352
Deposit date:
2017-06-19

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