Journal article
A multiple phenotype imputation method for genetic studies
- Abstract:
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Genetic association studies have yielded a wealth of biologic discoveries. However, these have mostly analyzed one trait and one SNP at a time, thus failing to capture the underlying complexity of these datasets. Joint genotypephenotype analyses of complex, high-dimensional datasets represent an important way to move beyond simple GWAS with great potential. The move to high-dimensional phenotypes will raise many new statistical problems. In this paper we address the central issue of missi...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Accepted manuscript, pdf, 1.6MB)
-
(Accepted manuscript, pdf, 3.3MB)
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- Publisher copy:
- 10.1038/ng.3513
Authors
Funding
+ Wellcome Trust
More from this funder
Funding agency for:
Dahl, A
Grant:
099680/Z/12/Z
090532/Z/09/Z
Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 48
- Issue:
- 4
- Pages:
- 466–472
- Publication date:
- 2016-02-22
- DOI:
- EISSN:
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1546-1718
- ISSN:
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1061-4036
Item Description
- Pubs id:
-
pubs:597462
- UUID:
-
uuid:883b3eb6-d4b6-4cae-9101-7c15aa94bead
- Local pid:
- pubs:597462
- Source identifiers:
-
597462
- Deposit date:
- 2016-01-26
Terms of use
- Copyright holder:
- Dahl et al
- Copyright date:
- 2016
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Nature Publishing Group at: https://doi.org/10.1038/ng.3513
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