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Journal article

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial.

Abstract:

Background

If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the longterm effects of successful CEA.

Methods

Between 1993 and 2003, 3120 asymptomatic patients from 126 centres in 30 countries were allocated equally, by blinded minimised randomisation, to immediate CEA (median delay 1 month [IQR 0·3–2·5]) or to...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s0140-6736(10)61197-x

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
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Medical Research Council More from this funder
Stroke Association More from this funder
BUPA Foundation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet (London, England) Journal website
Volume:
376
Issue:
9746
Pages:
1074-1084
Publication date:
2010-09-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Source identifiers:
79855
Language:
English
Keywords:
Pubs id:
pubs:79855
UUID:
uuid:8839f0fd-1f7d-4458-bc7a-5e3b7ae73c9f
Local pid:
pubs:79855
Deposit date:
2012-12-19

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