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Metformin and prostate cancer: a new role for an old drug

Abstract:

Since epidemiological studies first demonstrated a potential positive effect of metformin in reducing cancer incidence and mortality, there has been an increased interest in not only better understanding metformin's mechanisms of action but also in exploring its potential anti-cancer effects. In this review, we aim to summarise the current evidence exploring a role for metformin in prostate cancer therapy.Preclinical studies have demonstrated a number of antineoplastic biological effects via ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s11934-017-0693-8

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Department:
Oxford, MSD, Surgical Sciences
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Department:
St Edmund Hall
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Department:
Oxford, MSD, Surgical Sciences
Publisher:
Springer US Publisher's website
Journal:
Current Urology Reports Journal website
Volume:
18
Issue:
6
Pages:
Article: 46
Publication date:
2017-04-25
DOI:
EISSN:
1534-6285
ISSN:
1527-2737
Pubs id:
pubs:695438
URN:
uri:87c64e69-d8b0-41bc-8913-16ae352c2476
UUID:
uuid:87c64e69-d8b0-41bc-8913-16ae352c2476
Local pid:
pubs:695438
Language:
English
Keywords:

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