- Abstract:
-
BACKGROUND: An understanding of the mechanisms mediating protective immunity against malaria in humans is currently lacking, but critically important to advance the development of highly efficacious vaccines. Antibodies play a key role in acquired immunity, but the functional basis for their protective effect remains unclear. Furthermore, there is a strong need for immune correlates of protection against malaria to guide vaccine development. METHODS: Using a validated assay to measure opsonic...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer Reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.2mb)
-
- Publisher copy:
- 10.1186/1741-7015-12-108
-
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- Publisher:
- BioMed Central Ltd. Publisher's website
- Journal:
- BMC medicine Journal website
- Volume:
- 12
- Issue:
- 1
- Pages:
- Article no. 108
- Publication date:
- 2014
- DOI:
- EISSN:
-
1741-7015
- ISSN:
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1741-7015
- URN:
-
uuid:87ae4f27-6282-4652-997d-3c71d992af75
- Source identifiers:
-
478263
- Local pid:
- pubs:478263
- Language:
- English
- Keywords:
- Copyright holder:
- Osier et al.
- Copyright date:
- 2014
- Notes:
- Copyright 2014 Osier et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Journal article
Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria.
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