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The Neurology and Neurosurgery Interest Group (NANSIG)—ten years of cultivating interest in clinical neurosciences

Abstract:
Given its proximity to the central nervous system, surgical site infections (SSIs) after craniotomy (SSI-CRAN) represent a serious adverse event. SSI-CRAN are associated with substantial patient morbidity and mortality. Despite the recognition of SSI in other surgical fields, there is a paucity of evidence in the neurosurgical literature devoted to skin closure, specifically in patients with brain tumors. The primary objective of this service evaluation is to ascertain the incidence and the risk factors associated with SSI-CRAN. The secondary objectives would be a) to ascertain the incidence of SSI-CRAN in sutured versus stapled wounds, after accounting for patient, surgical and hospital confounders of SSI-CRAN and b) to determine the percentage of patients with gliomas that begin adjuvant oncological treatment in patients with infection versus those without infection. Methods Surgical Site Infection after Craniotomy in Neuro-Oncology (SINO) is a international prospective multicentre service evaluation that will include patients with an intracranial neoplasm, both primary and secondary neoplasms, treated with cranial surgery (including biopsy). Consecutive paediatric (st October 2024 and 1st December 2024 will be included. Prospective data will be collected with a follow-up of 90 days
Publication status:
Published
Peer review status:
Peer reviewed

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Authors

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Role:
Author
ORCID:
0000-0001-8762-6986
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Role:
Author
ORCID:
0000-0002-7097-0948
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Role:
Author
ORCID:
0000-0002-9153-3077
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0001-6553-3842


Publisher:
Springer
Journal:
Acta Neurochirurgica More from this journal
Volume:
164
Issue:
4
Pages:
937-946
Publication date:
2022-01-18
DOI:
EISSN:
0942-0940
ISSN:
0001-6268


Language:
English
Keywords:
Pubs id:
1236131
Local pid:
pubs:1236131
Source identifiers:
W4205636170
Deposit date:
2026-04-09
ARK identifier:
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