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Journal article

Smart superglue in streptococci? The proof is in the pulling

Abstract:

Gram-positive bacteria use reactive thioester-containing proteins to form covalent bonds, which may enable strong adhesion to host surfaces, but how these proteins selectively adhere to different surfaces is not clear. The Editors' Pick by Echelman et al. applied single-molecule force spectroscopy to show that an adhesin protein can regenerate its thioester in the absence of pulling. This selective interaction would represent a new principle of mechanical proof-reading, whereby only reactions...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1074/jbc.H117.777466

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Institution:
University of Oxford
Oxford college:
Worcester College
Role:
Author
University of Oxford More from this funder
Publisher:
American Society for Biochemistry and Molecular Biology Publisher's website
Journal:
Journal of Biological Chemistry Journal website
Volume:
292
Issue:
21
Pages:
8998-8999
Publication date:
2017-05-26
Acceptance date:
2017-04-14
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
Source identifiers:
698074
Language:
English
Pubs id:
pubs:698074
UUID:
uuid:87868d83-62bd-4803-83e1-df62d58722f9
Local pid:
pubs:698074
Deposit date:
2017-06-03

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