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Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinants.

Abstract:

Red blood cells that are infected with the malaria parasite Plasmodium falciparum express new antigens on their surface. In a study of these antigens in the erythrocytes of naturally infected children in the Gambia, an antibody-mediated agglutination assay revealed an extreme degree of antigenic diversity. Serum samples from each of ten children in the convalescent stage of malaria infection reacted with infected cells from the same child but generally not with infected cells from the other c...

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Publisher copy:
10.1126/science.2417315

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
Science (New York, N.Y.)
Volume:
231
Issue:
4734
Pages:
150-153
Publication date:
1986-01-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:8772771a-7389-48d6-8db2-e0b8cf454d83
Source identifiers:
221837
Local pid:
pubs:221837

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