Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation
The purpose of this exploratory study was to investigate the combination of a radiopharmaceutical, nanoparticles and ultrasound (US) enhanced delivery to develop a clinically viable therapeutic strategy for tumours overexpressing the epidermal growth factor receptor (EGFR). Molecularly targeted radionuclides have great potential for cancer therapy but are sometimes associated with insufficient delivery resulting in sub-cytotoxic amounts of radioactivity being delivered to the tumour. Liposome...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Accepted manuscript, 1.3MB)
- Publisher copy:
- Copyright holder:
- Elsevier B.V.
- Copyright date:
- Rights statement:
- © 2020 Elsevier B.V. All rights reserved.
- This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.jconrel.2019.12.045
If you are the owner of this record, you can report an update to it here: Report update to this record