Journal article
Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation
- Abstract:
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The purpose of this exploratory study was to investigate the combination of a radiopharmaceutical, nanoparticles and ultrasound (US) enhanced delivery to develop a clinically viable therapeutic strategy for tumours overexpressing the epidermal growth factor receptor (EGFR). Molecularly targeted radionuclides have great potential for cancer therapy but are sometimes associated with insufficient delivery resulting in sub-cytotoxic amounts of radioactivity being delivered to the tumour. Liposome...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, 1.3MB)
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- Publisher copy:
- 10.1016/j.jconrel.2019.12.045
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Controlled Release Journal website
- Volume:
- 319
- Pages:
- 222-233
- Publication date:
- 2019-12-28
- Acceptance date:
- 2019-12-27
- DOI:
- EISSN:
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1873-4995
- ISSN:
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0168-3659
- Source identifiers:
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1080762
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:1080762
- UUID:
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uuid:8764400c-27dc-4f3e-990a-d21dbeb0812b
- Local pid:
- pubs:1080762
- Deposit date:
- 2020-01-03
Terms of use
- Copyright holder:
- Elsevier B.V.
- Copyright date:
- 2020
- Rights statement:
- © 2020 Elsevier B.V. All rights reserved.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.jconrel.2019.12.045
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