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Journal article

Substituted pyrroles via olefin cross-metathesis.

Abstract:
Olefin cross-metathesis (CM) provides a short and convenient entry to diverse trans-γ-aminoenones. When exposed to either acid or Heck arylation conditions, these intermediates are converted to mono-, di-, or trisubstituted pyrroles. The value of this chemistry is demonstrated by its application to the tetrasubstituted pyrrole subunit of Atorvastatin.
Publication status:
Published

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Publisher copy:
10.1021/ol101681r

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Organic letters More from this journal
Volume:
12
Issue:
18
Pages:
4094-4097
Publication date:
2010-09-01
DOI:
EISSN:
1523-7052
ISSN:
1523-7060


Language:
English
Pubs id:
pubs:67461
UUID:
uuid:873418f7-3406-493b-8e27-31257bf8c02a
Local pid:
pubs:67461
Source identifiers:
67461
Deposit date:
2012-12-19

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