Journal article
Oligomerization driven by phase separation
- Abstract:
- Chemical reactions occurring within liquid‐liquid phase separated systems drive numerous biological processes and have likely been involved in the emergence of first cellular compartments. Herein we report a reaction whose product distribution is drastically affected by the presence of a liquid‐liquid interface. Under phase separated conditions, the system produces a dynamic library of increasingly complex oligomeric structures. This reactivity is in sharp contrast to results under homogeneous conditions; when there is no phase separation only two thermodynamically stable products are formed. The reactivity observed using phase separated conditions stems from generating a dynamic out‐of‐equilibrium self‐assembling system. This work shows that relatively complex oligomeric products that would not be otherwise easily accessible can be made by biphasic out‐of‐equilibrium processes.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Preview, Accepted manuscript, pdf, 883.4KB, Terms of use)
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- Publisher copy:
- 10.1002/syst.201900059
Authors
- Publisher:
- Wiley
- Journal:
- ChemSystemsChem More from this journal
- Volume:
- 2
- Issue:
- 5
- Article number:
- e1900059
- Publication date:
- 2020-02-03
- Acceptance date:
- 2020-01-22
- DOI:
- ISSN:
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2570-4206
- Language:
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English
- Keywords:
- Pubs id:
-
1084849
- Local pid:
-
pubs:1084849
- Deposit date:
-
2020-02-04
- ARK identifier:
Terms of use
- Copyright holder:
- Wiley-VCH Verlag
- Copyright date:
- 2020
- Rights statement:
- © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Wiley at https://doi.org/10.1002/syst.201900059
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